Among many organic pesticides, organophosphorus chemicals have been believed to be almost nontoxic because they are not accumulative in the tissue. And therefore, organophosphorus chemicals have been used most frequently. However, some studies have reported quite many cases of farmers, cattle feeders and foresters who have been suffered from organophosphorus pesticides, and others have described on the incidence of agricultural pesticides ranging 20-45 % of chemical intoxication. Thus, it has been gradually recognized that the intoxication from organophosphorus pesticide needs to be reviewed.
This study is in this relevance, attempted to examine the effects of organophosphorous pesticide upon the stomach. In doing this, five different organophosphorus pesticides being used frequently in Korea have been selected. And they were divided into normal and experimental groups, and studied morphologically.
The results obtained from this experiment are as follows;
1) Light microscopically, swelling of the mucosal cells, congestion and areas of inflammatory cell collection in the stomach are observed in the groups of EPN and DDVP administered. In addition, ´hemorrhage of the gastric mucosa are found in the parathion administered groups.
2) Electron microscopically, swelling or ruptured mitochondria and partial detachment of microvilli in the stomach are observed in the groups of EPN and DDVP administered. Additionally, markdly ruptured mitochondria and partial detachment of microvilli in the stomach are visible in the parathion administered group.
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